What I Use
Since I a) get asked that a lot and b) Mathieu Tozer has a post with the same name, that gave me the inspiration and c) some people around me will get a shiny new Mac and d) some people actually read my blog (surprise!).
Edit: I just found my old post on the same topic. Have a look around there as well.
Bookmarks
del.icio.us and to retrieve them, Quicksilver
Blogging
Coding
FTP
Instant Messaging
Adium (preferably over Jabber), seldomly Skype; Colloquy for IRC
Layouting the written stuff
Note Taking
My hive mind and, though more and more less so, DevonThink
Notifications
Photos
Reading Word-Files from other people
Nisus Writer Express / NeoOffice
RSS
Shared Documents
Spreadsheets
Since my needs are modest, I can do with OmniOutliner
To Dos / GTD
Workout Log
A simple sheet of paper, residing at the gym … :)
Writing (Creative / Scientific)
And of course: there’s IUseThis as well …